By Ilka Gansera-Lévêque 
 • 
 August 12, 2018 
 
 Guest post by: Dr. Cath Dunnett of Independent Equine Nutrition (IEN).                                                                                                                    There are intrinsic contamination risks  associated with horse feed and supplements which have in recent years  been responsible for a series of post-race positives. Contamination of  feed principally occurs due to the accidental introduction of an  ingredient containing a naturally occurring prohibited substance. There  are many stages in feed production and accidental contamination could  happen at several stages, for example, contamination with weeds  containing prohibited substances during the growth of cereal or other  ingredients.                                                                                   Inadvertent  contamination could also occur during harvest through the sharing of  equipment or storage, or during cross-contamination during shipping or  transport to the mill. There is potentially an increased risk of such  contamination as a larger number of ingredients are sourced from across  the globe and feed and supplement production becomes a worldwide  operation.                                                                                                                                                                 Naturally Active Compounds                                                                                                                                            The feed industry takes the risk of  contamination incredibly seriously and strategies have been implemented  to reduce contamination risks from ingredients both produced at home and  imported. Broadly the feed industry has a very good knowledge where the  risks for contamination with prohibited substances lie, however, these  can be complicated when additives such as herbs, spices, or plant  extracts are used in feed or supplements. Here there are two key  considerations – firstly, many plants naturally contain  pharmacologically active compounds that could be considered as  prohibited substances. Secondly, the country of origin may lack  sufficiently thorough quality control systems.                                                                                                                    The post-race positives due to morphine  contamination of feed were reportedly due to poppy seed contamination of  one or more ingredients. It may be a surprise to many that  morphine-containing poppies had until recently been harvested in various  locations around the UK, under a specific license and strict control  and management, for the production of pharmaceuticals. A greater amount  of morphine is found within the poppy seed head, whereas the seeds  themselves contain only a very low level of morphine. It’s worth  mentioning that the commonly seen red field poppies do not present a  notable contamination risk, as they contain very low levels of morphine,  if any at all.                                                                                                                   Interestingly, in human food production,  fragments of poppy seeds and heads do infiltrate the food chain. Yet,  the European Food Standards Agency (EFSA) does not list morphine as an  undesirable substance and there remains no minimum legal limit for  morphine in human food.                                                                                                                                                                 Significant Physiological Levels In Racehorses                                                                                                                                            Whilst the potential for low residual  levels of morphine in the food chain may be physiologically  inconsequential to humans, it remains extremely problematic to trainers.  Morphine is a significant analgesic and therefore must be regulated in a  way that prevents its potential for abuse. Investigations into  contamination might successfully conclude that any post-race positive  test was as a result of feed contamination, however, it remains the  case, that the horse has raced with a level of the ‘drug’ in its system.                                                                                                                     Prohibited substance testing is  incredibly accurate and a positive post-race result will be returned on  minute levels. Whilst regulatory bodies over the world may choose to  take a pragmatic view, nevertheless, there is no ‘official’ threshold  for morphine in post-race samples in racehorses, therefore, a line must  be drawn. For welfare reasons, there is no scientific evidence to allow  us to determine an acceptable level where no physiological effect is  confirmed.                                                                                                                                                                 Scheme Accreditation                                                                                                                                            The UK feed industry developed a quality  assurance code as a risk management measure to reduce the risk of  prohibited substances entering equine feed and to safeguard the  interests of consumers and feed producers and suppliers.                                                                                                                    The aim of any such quality assurance  scheme is to understand where the risks lie within each part of the  supply chain and then how to mitigate those risks. Here are a few areas  where such a scheme can assist:                                                                                                                                              Ensuring a long-term relationship with suppliers.                                                                                                                                 Using an appropriately accredited manufacturing facility.                                                                                                                                  Ensuring that everyone involved in the  supply and manufacturing chain, including, farmers, harvest contractors,  processors, hauliers, storage suppliers, trainers and stable staff  understand the importance and the risks posed by prohibited substances  and the consequences of minute levels of contamination.                                                                                                                                  Encouraging collaboration between  different manufacturers, so that concerns regarding ingredients or  products, can be shared following analysis.                                                                                                                                 Ensuring that marketing claims regarding prohibited substances are factual and not misleading.                                                                                                                                            Accredited companies are likely to be  audited annually, to ensure their compliance with the scheme and that  robust quality control systems remain in place to reduce the risk of  contamination by prohibited substances.                                                                                                                                                                 Gathering Information                                                                                                                                            In addition to the efforts made by the  equine feed industry, trainers themselves have a responsibility to  understand the contamination risks and actively manage them. After all,  it’s the trainer’s reputation and livelihood that is at stake. Trainers  may receive some advice on this from their regulatory bodies and in the  UK whilst attending the BHA trainer licensing course and any NTF  seminars on the subject.                                                                                                                    So far as is possible, trainers must be  totally aware of the constituent parts of everything that is fed to  their horses. This information is readily available, as it’s a legal  requirement for companies to provide such details on the packaging.                                                                                                                    Trainers would also be advised to enquire  about the quality control systems that their manufacturer has in place  to reduce the risk of contamination with prohibited substances. This  could involve comprehensive risk assessments, raw material traceability  and testing of both the ingredients and the finished product in some  cases. Regardless of the size of the business, or their supply  structure, all companies should have a robust system of traceability and  quality control. For instance, my own company Racing Blue, follow a  thorough quality control program in the manufacture of STORM                                                                             ®                                                                               Equus that includes every batch of each raw material and finished  product being tested for a wide range of prohibited substances prior to  release for sale.                                                                                                                   Where a trainer uses a product  manufactured abroad, sufficient questions of the importer/marketer  should be asked, to ensure their processes match those in the home  country. For instance, certain substances that are allowable in  agricultural feed production in other countries, may be regarded a  prohibited under the Rules of Racing in the home country.                                                                                                                                                                 Daily Management Procedures                                                                                                                                             It’s advisable for trainers to implement  additional feed procedures in the yard, such as maintaining a  comprehensive list of feedstuffs given to individual horses. This proves  extremely useful should a post-race sample return as positive. Further  to this, keeping an accurate record of delivery dates, batch numbers and  invoices, as well as retaining a copy of all associated delivery notes  and other paperwork, provides further evidence, if needed, to establish  the route of contamination. Better still, retaining samples of each  batch of feed and supplement for about 3 months is an excellent process  to implement, as this is the period of time over which a post-race  positive is possible and the consequent regulatory process will last.  Representative samples of feed (500g) and a supplement (100g) should be  stored in a sealed plastic bag and labelled with the product name, batch  code and purchase date. Should an investigation be necessary, the  record keeping along with the feed samples will provide vital evidence.  Feed or supplement manufacturers should also retain samples for  re-examination if a problem arises, however, it’s a sensible precaution  for trainers to do the same.                                                                                                                   Quality control processes and  accreditation schemes have brought considerable benefit to the racing  industry, however, historical positive cases with morphine and other  substances demonstrate that accidental contamination can still happen,  and there are always further improvements that can be made. Equally  however, trainers have a pivotal role and must ensure they keep informed  and up to date, so that they’re able to make the best possible feeding  and feed management choices.                                                                                                                   You can find out more about feed analysis on the IEN website.